covid vaccine panic attack side effect

Article Clin Imaging. Comput Struct Biotechnol J. Possible side effects: Pain, redness, or swelling at the site where the shot was administered, and/or tiredness, headache, muscle pain, chills, fever, or nausea throughout the rest of the body. fatigue. 2014;13(3):21524. Reporting rates were calculated using the approximate number of doses of each vaccine administered during the respective analysis periods. Descriptive analyses of VAERS data were stratified by vaccine type, sex, and age group. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. of pages found at these sites. Google Scholar, who.int. Al-Mashdali AF, Ata YM, Sadik N. Post-COVID-19 vaccine acute hyperactive encephalopathy with dramatic response to methylprednisolone: a case report. The findings in this report are subject to at least three limitations. 2021;14(7): e243829. Although four of the five mass vaccination sites that reported anxiety-related events temporarily suspended COVID-19 vaccination, none of the reports to VAERS was considered serious. We take your privacy seriously. ** The population receiving Janssen COVID-19 likely differs from the population who received influenza vaccine in during the 201920 season; however, the latter is representative of a typical adult population seeking routine vaccination with a single-dose vaccine. Fever. Approximately one quarter of the syncopal and other anxiety-related events after receipt of Janssen COVID-19 vaccine described in this report occurred in persons who reported a history of similar events after vaccination. As of November 2022, 630.3 million people have been diagnosed with COVID-19 and 6.58 million deaths worldwide, according to WHO figures [2]. Contact your healthcare provider. 2021;24: e01143. According to reports published in the VAERS database, COVID-19 vaccines have several local and systemic neurological complications that occur in different people, from mild to severe, depending on age, sex, history of the disease, and pre-existing immunity [7]. Neurological complications of COVID-19: Guillain-Barre syndrome following Pfizer COVID-19 vaccine. Thread starter LuteHawk; Start date Feb 5, 2021; Prev. mmwrq@cdc.gov. 2021;64(1):E1. Woo CJ, Chou OHI, Cheung BMY. The most commonly reported side effects were: Fever Headache Fatigue (tiredness) Pain at the injection site Helpful tips to relieve side effects Adults To relieve pain or swelling on the arm where you got the shot: Apply a clean, cool, wet washcloth over the area. 2023 BioMed Central Ltd unless otherwise stated. COVID-19 vaccines can cause mild side effects after the first or second dose, including: Pain, redness or swelling where the shot was given Fever Fatigue Headache Muscle pain Chills Joint pain Nausea and vomiting Swollen lymph nodes Feeling unwell Most side effects go away in a few days. Because the results of the phase 4 studies are the proper criteria for how the vaccine works in the real world [5]. Centers for Disease Control and Prevention. Vogrig A, Janes F, Gigli GL, Curcio F, Del Negro I, DAgostini S, Fabris M, Valente M. Acute disseminated encephalomyelitis after SARS-CoV-2 vaccination. This content does not have an Arabic version. Possible causes of COVID-19. COV2. The National Alliance on Mental Health suggest . First, VAERS is a passive surveillance reporting system and subject to underreporting (1). Venous sinus thrombosis is associated with excessive coagulation. Post-COVID conditions among adult COVID-19 survivors aged 18-64 and 65 years United States, March 2020 November 2021. Wichova H, Miller ME, Derebery MJ. Clin Med (Northfield Il). Neurol Sci. MMWR Morb Mortal Wkly Rep 2021;70:685688. Unlike currently used vaccines, which use synthetic materials or adenovirus to package and deliver antigens, the researchers from Indian Institute of Technology (IIT), Delhi have taken a step forward towards next-generation vaccine for Covid-19, the study said. ** CDC provided recommendations on who should be vaccinated first because COVID-19 vaccine supply was initially limited. Adverse effects of vaccines: evidence and causality. Post-COVID conditions: Overview for healthcare providers. Among the 653 VAERS reports of syncope, 327 (50%) occurred in women. Neurol Sci. Overall, 64 anxiety-related events, including 17 reports of syncope (fainting), an anxiety-related event, among 8,624 Janssen COVID-19 vaccine recipients, were reported from these sites for vaccines administered during April 79. This conversion might result in character translation or format errors in the HTML version. Post COVID-19 vaccination-associated neurological complications. Finally, the Janssen COVID-19 vaccine was not directly compared with other currently available COVID-19 vaccines and instead was compared with influenza vaccine administered during the 201920 season. Summary: A number of videos have surfaced on popular channels showing people experiencing some adverse effects following the coronavirus vaccine.Researchers say some of the cases could be related to functional neurological disorder, a common neuropsychological condition. As a follow-up to these interviews, CDC reviewed VAERS reports received during March 2April 22, 2021, for adverse events associated with receipt of Janssen COVID-19 vaccine doses administered during March 2April 12. Corresponding author: Anne M. Hause, voe5@cdc.gov. The process that causes the disorder is probably explained by the fact that the varicella-zoster virus CD8+killer cells, after vaccination, are temporarily unable to control VZV due to the extensive change of simple CD8+cells to the COVID-19 virus CD8+killer cells. Google Scholar. In some people, post-COVID-19 syndrome lasts months or years or causes disability. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Begin Exploring Women's Health Solutions at Mayo Clinic Store. Cookies used to make website functionality more relevant to you. RH: carried out the searched publications, classified the documents, and wrote the manuscript draft. headache. 2021. https://doi.org/10.1002/alr.22809. A review of neurological side effects of COVID-19 vaccination, https://doi.org/10.1186/s40001-023-00992-0, https://doi.org/10.1007/s10072-021-05662-9, https://doi.org/10.1038/s41598-022-17514-3, https://doi.org/10.1007/s13760-021-01775-2, https://doi.org/10.9734/ijmpcr/2021/v14i130124, https://doi.org/10.1007/s12024-021-00440-7, https://doi.org/10.1016/j.nrleng.2021.05.002, https://doi.org/10.6061/clinics/2021/e3286, https://doi.org/10.1080/14992027.2021.1931969, https://doi.org/10.1136/postgradmedj-2021-141022, https://doi.org/10.1007/s00415-021-10780-7, https://doi.org/10.1016/j.nrleng.2021.04.002, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. Mild neurological effects of the COVID-19 vaccine include weakness, numbness, headache, dizziness, imbalance, fatigue, muscle spasms, joint pain, and restless leg syndrome are more common, while tremors, tinnitus, and herpes zoster are less common. Since April 2021, some people have developed myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the lining outside the heart) after receiving the Pfizer-BioNTech or Moderna coronavirus vaccines in the United States, according to the U.S. Centers for Disease Control and Prevention (CDC). As of November 2021, 11 candidate vaccines for COVID-19 have been approved by the World Health Organization for mass vaccination after leaving phase 3 of clinical studies. For example, if you fear getting the vaccine because you might have an allergic reaction, consult the facts: one study of the Pfizer vaccin e showed . Many. New Engl J Med. Centers for Disease Control and Prevention. Chills and swollen lymph nodes can also occur. Centers for Disease Control and Prevention. It isn't clear how long these effects might last. My fourth idea is that this is a result of fever which can cause delirium, breaks of . 2021;269(3):112132. On April 30, 2021, this report was posted online as an MMWR Early Release. 2021;21(4):4502. 2021;19(7):17715. I truly believe this is a side effect of the vaccine. Santovito LS, Pinna G. Acute reduction of visual acuity and visual field after Pfizer-BioNTech COVID-19 vaccine 2nd dose: a case report. The symptoms usually peak in about ten minutes and then begin to subside. Among people age 65 and older, 1 in 4 has at least one medical condition that might be due to COVID-19. On the other hand, women have the highest incidence of neurological complications because they induce a stronger immune response against foreign antigens, which can lead to the targeting of self-antigens and lead to autoimmune disorders [9]. Privacy Therefore, it is possible that some persons seeking Janssen COVID-19 vaccination could be more highly predisposed to anxiety-related events after being vaccinated. The vaccine cannot cause a COVID-19 infection, so symptoms mean your body is building a healthy immune response. Clin Neurol Neurosurg. Saeed S, et al. Report an Adverse Event using the VAERS online form or the downloadable PDF. Finsterer J. Immunization stress-related response: a manual for program managers and health professionals to prevent, identify and respond to stress related responses following immunization. 2021. https://doi.org/10.7759/cureus.16172. They help us to know which pages are the most and least popular and see how visitors move around the site. A virus that was much more contagious than SARS Covid-1 and spread to different parts of the world in a short time. In a short-term sense, you may find it useful to talk to somebody who can provide you non-judgemental support, advice, and immediate assistance. 2021;93(12):658894. In December 2019, the SARS Covid-2 virus was introduced to the world. Garca-Azorn D, Do TP, Gantenbein AR, Hansen JM, Souza MNP, Obermann M, Pohl H, Schankin CJ, Schytz HW, Sinclair A. Sect. BMJ Case Reports CP. Vaccine reactivity has been linked to a temporary increase in inflammatory cytokines that act on blood vessels, muscles, and other tissues. CAS Like a fish yanked from a pond, I flopped onto a hard plastic chair . Neurol Sci. Your Side Effects Don't Go Away iStock If any of the "normal" side effectsincluding pain, redness or swelling in the injection area or fatigue, headache, muscle pain, chills, fever, nauseadon't seem to go away after a few days, you should call your doctor ASAP. PubMed Article COV2. 2021;67: 102540. Tidsskrift for Den norske legeforening. References to non-CDC sites on the Internet are Transverse myelitis has been observed after injection of mRNA and adenovirus-based vaccines, and it is noteworthy that mRNA-based vaccines can cause exacerbation or early manifestation of MS and neuromyelitis optica. MMWR Morbidity and Mortality Weekly Report. Another CDC report released Friday looked at side effects reported by more than 300,000 J&J vaccine recipients. Ann Neurol. Jain E, Pandav K, Regmi P, Michel G, Altshuler I. Facial diplegia: a rare, atypical variant of Guillain-Barr syndrome and Ad26. 2021;21(5): e535. "Reassuring the public that everything is being done . Anxiety-related events, including syncope, can occur immediately after vaccination with any vaccine and might be caused by anxiety about receiving an injection (3). Otologic manifestations after COVID-19 vaccination: the house ear clinic experience. Olfactory dysfunction ranges from a lack of sense of smell to an olfactory hallucination (phantosmia) that results from a bilateral disturbance or enhancement of the olfactory pathway and the olfactory bulb. Acute disseminated encephalomyelitis-like presentation after an inactivated coronavirus vaccine. All HTML versions of MMWR articles are generated from final proofs through an automated process. Anne M. Hause, PhD1; Julianne Gee, MPH1; Tara Johnson, MPH, MS1; Amelia Jazwa, MSPH1; Paige Marquez, MSPH1; Elaine Miller, MPH1; John Su, MD, PhD1; Tom T. Shimabukuro, MD1; David K. Shay, MD1 (View author affiliations). * Each VAERS report might be assigned more than one MedDRA preferred term. The Pfizer, Moderna, and Novavax vaccines have been shown to be at. J Neurol. Guillain-Barr syndrome after COVID-19 vaccine: should we assume a causal Link? Four of the five sites temporarily closed while an investigation took place. Amyotrophic neuralgia secondary to Vaxzevria (AstraZeneca) COVID-19 vaccine. It was such a strange, unfamiliar sensation that I didn't realize what was happening. Find more COVID-19 testing locations on Maryland.gov. Hearing disorders can vary from hearing loss to tinnitus and dizziness. If you had COVID-19 before being vaccinated, the first injection may cause more noticeable side effects than for people who have not had the coronavirus. 1; 2; First Prev 2 of 2 Go to page. Adenovirus-based vaccines are at the forefront of causing this complication due to the transfer of the nucleic acids encoding the viral spike (S) protein. Crawford NW, Clothier HJ, Elia S, Lazzaro T, Royle J, Buttery JP. At the same time, there are many reports of side effects after getting a COVID-19 vaccine. 2021. https://doi.org/10.2139/ssrn.3841558. Loharikar A, Suragh TA, MacDonald NE, et al. Thrombocytopenia with acute ischemic stroke and bleeding in a patient newly vaccinated with an adenoviral vector-based COVID-19 vaccine. The Covid-19 Vaccine Safety Technical (VaST) Work Group confirmed "data available to date suggest likely association" of myocarditis and pericarditis in people who get the Pfizer and Moderna jabs. Feelings of having a fast-beating, fluttering or pounding heartbeat, Severe or persistent headaches or blurred vision, Easy bruising or tiny blood spots under the skin near the injection site. Cureus. 2021;359: 577686. Rehabilitation after COVID-19 - Related information, Post-COVID Recovery - Related information, Post-COVID-19 syndrome could be a long haul (podcast) - Related information, Post-COVID-19 syndrome could be a long haul (podcast), Post-COVID conditions - Related information. Post-vaccine symptoms are typically mild and resolve quickly without the need to use any medication. Accessed May 24, 2022. PubMed Central Myocarditis is more likely to occur as a result of COVID-19 infection than as a side effect of the vaccines. Another CDC report released Friday looked at side effects reported by more than 300,000 J&J vaccine recipients. Clin Park Relat Disord. Bells palsy following COVID-19 vaccination: a case report. You can review and change the way we collect information below. Six persons who received diphenhydramine or epinephrine at the vaccination visit were excluded because these events might have represented allergic reactions; none was classified as anaphylaxis. Hyperthermia, in turn, increases glial cell activity and increases bloodbrain barrier permeability. Also, there is ample evidence that the Pfizer and AstraZeneca vaccines are associated with optic nerve inflammation and vision disorders and are more common in middle-aged people [70]. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Tseng P-T, Chen T-Y, Sun Y-S, Chen Y-W, Chen J-J. Side effects of COVID-19 vaccination have been reported more frequently in people with a history of immune-related diseases or who are more sensitive to age and physiological conditions. What a timely discovery! Saving Lives, Protecting People, US case reports of cerebral venous sinus thrombosis with thrombocytopenia after Ad26.COV2.S vaccinationMarch 2 to April 21, 2021, https://www.meddra.org/how-to-use/basics/hierarchy, https://www.cdc.gov/flu/fluvaxview/coverage-1920estimates.htm, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations.html, https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html, https://doi.org/10.1016/j.vaccine.2015.07.035, https://www.who.int/publications/i/item/10665330277, https://doi.org/10.1016/j.vaccine.2017.11.017, https://doi.org/10.5694/j.1326-5377.2011.tb04138.x, Centers for Disease Control and Prevention, U.S. Department of Health & Human Services, Cases per 1,000 vaccinated, total (per day), Reported history of anxiety related to needles or medical visits. MMWR and Morbidity and Mortality Weekly Report are service marks of the U.S. Department of Health and Human Services. COVID-19 vaccine-induced encephalitis and status epilepticus. Chiu H-H, Wei K-C, Chen A, Wang W-H. J Neurol Sci. George G, Friedman KD, Curtis BR, Lind SE. 2021. https://doi.org/10.6061/clinics/2021/e3286. 241(d); 5 U.S.C. Because the Janssen COVID-19 vaccine is administered as a single dose, this vaccine might be a more attractive option for persons who have needle aversion. https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects.html. 3501 et seq. Corra DG, Caete LAQ, Dos Santos GAC, de Oliveira RV, Brando CO, da Cruz Jr LCH. Int J Res Pharma Sci. In addition to the anxiety-related events reported by the five mass vaccination sites, review of all VAERS reports containing the MedDRA term syncope or syncope vasovagal after vaccination with Janssen COVID-19 vaccine during March 2April 11 identified 653 eligible reports (reports missing information regarding time of vaccine receipt and event were not included) (Table 2). 2021;208: 106887. Iba T, Levy JH, Warkentin TE. Therefore, physicians and personnel of medical centers related to these patients should recognize these complications and intervene as soon as possible. In November 2021 in The New England Journal of Medicine, he proposed that an autoimmune mechanism triggered by the SARS-CoV-2 spike protein might explain both Long Covid symptoms and some rare vaccine side effects, and he called for more basic research to probe possible connections. Muscle and joint pain. painful, swollen lymph nodes in the arm where the vaccine was injected. 2022. https://doi.org/10.1038/s41598-022-17514-3. 2021;384(23):220211. The COVID-19 vaccine-related convulsions can be attributed to the synthesis and release of spike proteins, which cause severe inflammation and hyperthermia. Learn more: Vaccines, Boosters & Additional Doses | Testing | Patient Care | Visitor Guidelines | Coronavirus. 2021; doi:10.1097/HJH.0000000000002819. Neurologia (Barcelona, Spain). In addition, in mass vaccination situations, an anxiety-related event witnessed by others on-site or reported through media coverage might provoke additional anxiety-induced episodes (4). In fact, the viral antigens of the vaccine stimulate an immunological response in the spinal cord [62]. The most important and most common complications are cerebral venous sinus thrombosis (more about AstraZeneca), transverse myelitis (more about Pfizer, Moderna, AstraZeneca, and Johnson & Johnson), Bell's palsy (more about Pfizer, Moderna, AstraZeneca), GBS (more about Pfizer, AstraZeneca, and Johnson & Johnson), and the first manifestation of MS (more about Pfizer). i'm on . Neurological side effects of SARS-CoV-2 vaccinations. Other tips to combat anxiety over the COVID vaccine: Check your imagination: COVID vaccine anxiety is often fueled by "what-if's"imagined scenarios of the many ways events can head south. Persons with allergic-like symptoms and those who received diphenhydramine or epinephrine were excluded. Thirteen patients were transported to an emergency department for further medical evaluation; all five patients with available follow-up information were released later that day. But the people of developed countries are still hesitant to take vaccines. Research, Review, and Case Report articles related to adverse effects of COVID-19 vaccination from 2020 to February 2022 were searched and reviewed in Google Scholar, PubMed, and NCBI databases. COVID-19 vaccines for kids: What you need to know, COVID-19 vs. flu: Similarities and differences. The information you provide and any test results will help your health care provider come up with a treatment plan. Burrows A, Bartholomew T, Rudd J, Walker D. Sequential contralateral facial nerve palsies following COVID-19 vaccination first and second doses. 2021;2(4):16971. statement and 2021;96(8):E3013. The most commonly reported symptoms of post- COVID-19 syndrome include: Fatigue Symptoms that get worse after physical or mental effort Fever Lung (respiratory) symptoms, including difficulty breathing or shortness of breath and cough Other possible symptoms include: Psychologists say people with serious COVID-19 cases may be at risk for. For all four vaccines, pain at the injection. and/or the original MMWR paper copy for printable versions of official text, figures, and tables. Ann Neurol. Muscle aches. Herein, we have provided a comprehensive review of documents reporting neurological side effects of COVID-19 vaccines in international databases from 2020 to 2022 and discussed neurological disorders possibly caused by vaccination. Anxiety-related events, including syncope, occurring soon after COVID-19 vaccination could raise concern among other vaccine recipients and staff members, particularly in a mass vaccination setting. Ozonoff A, Nanishi E, Levy O. Bells palsy and SARS-CoV-2 vaccines. J Neuroimmunol. JAMA. Bell's palsy and small fiber neuropathy are more commonly observed in mRNA-based vaccines [63, 64]. Waheed S, Bayas A, Hindi F, Rizvi Z, Espinosa PS. 2021;397(10269):99111. O. Ozzy4335 HR MVP. The effects also could lead to the development of new conditions, such as diabetes or a heart or nervous system condition. Events that occurred off-site or 1 hour after vaccine administration and those in persons who received diphenhydramine or epinephrine at the vaccination visit were not included. Cases per 100,000 persons vaccinated. "We don't know why that is, how long these symptoms will last or if there are effective ways to treat them. These activities were reviewed by CDC and were conducted consistent with applicable federal law and CDC policy.. Syncope and other anxiety-related events can occur after vaccination and have been reported to the Vaccine Adverse Events Reporting System (VAERS) for other vaccines. Median patient age was 36 years (range=1877 years). endorsement of these organizations or their programs by CDC or the U.S. * Site C was located on a college campus that was vaccinating students. An anxiety-related adverse event was defined as any of the following occurring in a person during the 15-minute postvaccination observation period at one of the five sites reporting these events: tachycardia, hyperventilation, dyspnea, chest pain, paresthesia, light-headedness, hypotension, headache, pallor, or syncope. Acute transverse myelitis associated with COVID-19 vaccine: a case report. Who Had Serious Side Effects from Covid 19 Vaccine? pain at the site of the injection. Sputnik-V reactogenicity and immunogenicity in the blood and mucosa: a prospective cohort study. part 46, 21 C.F.R. Complications usually appear within one day to 1month after injection and are usually acute, transient, and self-limiting, but in severe cases lead to hospitalization and intensive care [8]. Classification of neurological complications observed after COVID-19 vaccination. COV2.S vaccination. Finsterer J. 2021;14(7): e243975. 2021;9(9):1008. Five mass vaccination sites reported 64 anxiety-related events, including 17 events of syncope (fainting) after receipt of Janssen COVID-19 vaccine. Baldelli L, Amore G, Montini A, Panzera I, Rossi S, Cortelli P, Guarino M, Rinaldi R, DAngelo R. Hyperacute reversible encephalopathy related to cytokine storm following COVID-19 vaccine. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The proposed mechanism for thrombocytopenia is the synthesis of IgG antibodies against platelet factor 4 (PF4), which activates platelets and blood clots in large venous arteries [28]. 2021;42(11):43979. Coronavirus vaccinations per country over time One model suggests that a combination of the slow vaccine rollout, the decrease in social distancing seen, and the spread of much more contagious forms of the virus could result in 300,000 more deaths in the U.S. over the next three months. A third reported fever or chills, and about a fifth said they were nauseous. Google Scholar. Keywords used for this search included COVID-19, SARS-CoV-2, vaccination, side effects, complications, vascular thrombosis, thrombocytopenia, myelitis, demyelination, and all kind of mRNA vaccines, Adenovirus vaccine, Pfizer, AstraZeneca, Johnson & Johnson, Moderna, Sinovac, Sinopharm, Sputnik, and Covaxin. You may experience: trouble sleeping difficulty concentrating difficulty remembering things changes in mood flashbacks more breathlessness rapid shallow breathing difficulty slowing your breathing down chest pain racing thoughts The new report comes as the Israeli Ministry of Health finds a "likelihood of a link" between the second dose of the Covid-19 vaccine and myocarditis, most commonly among males ages 16 to 30 . CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Other side effects can include pain, redness or swelling at the injection site and possibly headache or nausea, the US Centers for Disease Control and Prevention said. As a follow-up to these interviews, CDC analyzed reports of syncope shortly after receipt of Janssen COVID-19 vaccine to the Vaccine Adverse Event Reporting System (VAERS), the vaccine safety monitoring program managed by CDC and FDA. Cureus. Inflammation and problems with the immune system can also happen. Both the Pfizer and the Moderna COVID-19 vaccinations involve two injections separated by several weeks. 2021;19:250817. 2021. https://doi.org/10.9734/ijmpcr/2021/v14i130124. Article Repajic M, Lai XL, Xu P, Liu A. Bells Palsy after second dose of Pfizer COVID-19 vaccination in a patient with history of recurrent Bells palsy. Google Scholar. These cookies may also be used for advertising purposes by these third parties. We are vaccinating all eligible patients. The CDC says people with allergies to certain foods, insects, latex and other common allergens can safely receive the COVID-19 vaccine. Despite concerns over Covid vaccines, most side effects occur with hours or weeks of having a jab. You will be subject to the destination website's privacy policy when you follow the link. 2021;111:21926. Ish S, Ish P. Facial nerve palsy after COVID-19 vaccinationA rare association or a coincidence. Ekizoglu E, Gezegen H, Yalnay Dikmen P, Orhan EK, Erta M, Baykan B (2021) The characteristics of COVID-19 vaccine-related headache: Clues gathered from the healthcare personnel in the pandemic. PubMed All COVID-19 vaccine recipients should be observed for at least 15 minutes after vaccination for anxiety-related and other events (e.g., anaphylaxis or immediate allergic reaction) occurring shortly after vaccination. Allen CM, Ramsamy S, Tarr AW, Tighe PJ, Irving WL, Tanasescu R, Evans JR. Guillain-Barr syndrome variant occurring after SARS-CoV-2 vaccination. McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH. Vaccine viral antigens activate platelets or indirectly cause blood to clot by activating complement pathways and increasing thrombin production. Although vaccines are now considered the best way to achieve collective safety and control mortality, due to the critical situation, these vaccines have been issued the emergency use licenses and some of their potential subsequence side effects have been . A single copy of these materials may be reprinted for noncommercial personal use only. Angana Chakrabarti 25 July, 2021 12:01 pm IST Notghi AA, Atley J, Silva M. Lessons of the month 1: Longitudinal extensive transverse myelitis following AstraZeneca COVID-19 vaccination. Ercoli T, Lutzoni L, Orofino G, Muroni A, Defazio G. Functional neurological disorder after COVID-19 vaccination. Delayed swelling, redness or a rash at the injection site. The chances of any of these side effects occurring after vaccination differ according to the specific vaccine.